HIV Clinical Trials Unit

of the

University of Pennsylvania

The AIDS Clinical Trials Unit (ACTU) at the University of Pennsylvania was established in 1992, in response to the AIDS crisis in Philadelphia and the United States. The unit is one of 32 university-based clinics, which make up the largest research organization in the world, the AIDS Clinical Trials Group (ACTG). It has been a leader in creating the standards of care for HIV infection and opportunistic diseases related to HIV / AIDS, by conducting studies to test new treatments. The ACTG is funded by the National Institutes of Health.

The AIDS Clinical Trials Group research focuses on:

  • Developing treatments based on better understanding of how HIV disease progresses.
  • Treatment strategies to decrease virus production and improve disease-free survival.
  • Rapid development of medicines to prevent or delay complications.
  • Recruitment and treatment of study participants who represent the range of people currently infected with HIV.
  • Treatments that improve quality of life for persons with HIV infection.

Mission Statement

The Mission of the University of Pennsylvania ACTU is to extend the survival and enhance the quality of life of people with HIV infection, through the further understanding of how the HIV virus causes HIV infection and its complications, and the development of new and improved treatments. We will strive to make HIV research available to all segments of the HIV community, to care for patients in research studies with compassion and with attention to their health as the fIrst priority, and to educate patients about HIV infection and its treatment so they may be more knowledgeable participants in their care.

Ebbing Lautenbach, MD, MPH, MSCE

Chief, Infectious Diseases Division


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